Oral Rush Desensitization to Egg: Efficacy
نویسنده
چکیده
hours of cow’s milk ingestion, skin prick tests $3 mm, and serum specific IgE levels $0.35 kU/L for whole cow’s milk, casein, a-lactalbumin, or b-lactoglobulin. Persistence of CMP allergy in the 4 weeks before tolerance induction was based on positive skin and serum testing and a positive double-blind placebo-controlled food challenge to cow’s milk. Exclusion criteria included anaphylactic shock after cow’s milk ingestion, non-IgEmediated or nonimmunologic adverse reactions, malignant or immunopathologic disease, immunosuppressive therapy, concurrent b-blocker use, and diseases contraindicating the use of epinephrine.
منابع مشابه
Oral rush desensitization to egg: efficacy and safety.
BACKGROUND Current management of egg allergy relies on egg elimination from the diet. It does not protect patients from reactions after accidental ingestion of the food and it has a negative influence on quality of life. To solve these problems, some desensitization protocols have been described that are safe and effective, but only one study of a rush regimen for egg with a small patient sampl...
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Background The oral tolerance induction to egg (OTI) is a promising treatment modality for egg allergy. Several small pilot studies have been published using different protocols and only one positive double-blind placebo-controlled food challenge have proved efficacy and relatively good tolerance. In all of them raw egg has been used. Recent studies suggest that a diet with heated egg in patien...
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We attempted an oral rush desensitization with mixed cow and sheep milk in a 6-year-old boy who had had adverse reactions to cow and goat milks. Skin prick tests and specific immunoglobulin (Ig) E to cow, sheep and goat milks were positive. The double-blind, placebo-controlled food challenge with cow milk was positive too. He underwent a 12-day sublingual-oral desensitization treatment with mix...
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BACKGROUND At present, the only treatment for food allergy is to avoid the allergy-causing food. Some trials of specific oral tolerance induction (SOTI) have been carried out, but the rate of tolerance induction was low despite long treatment periods, at least 3 months to several years. A new type of treatment is long desired. The objectives of this study are to perform our rush SOTI for school...
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