Bronchial Challenge Testing
نویسندگان
چکیده
Airways hyper-responsiveness (AHR) is found in almost every patient with asthma. The degree of AHR is variable between individuals with asthma and can correlate to the severity of the underlying asthma. Equally treatment of asthma can modify the degree of underlying AHR. Measures of Airway hyper-responsiveness or bronchial challenge testing are therefore important in both the assessment and management of asthma.
منابع مشابه
Occupational asthma in a pesticides manufacturing worker.
A 34-year-old chemical manufacturing worker had new onset of work-related asthma after several years of exposure to the fungicide, captafol. On specific bronchial challenge testing, he demonstrated a marked and persistent fall in FEV1. Cessation of exposure resulted in improved symptoms and pulmonary function. The delay in symptoms after several years of workplace exposure and the dual reaction...
متن کاملRelationship between Methacholine Challenge Testing and exhaled nitric oxide in adult patients with suspected bronchial asthma.
Usually, hyperresponsiveness to inhaled methacholine is considered closely associated with a diagnosis of bronchial asthma. Recently, it has been clearly pointed out that bronchial hyperreactivity (BHR) is not a constant feature of asthma and that this condition is not always related to airways inflammation. In the present study we evaluated 42 Patients (21 positive and 21 negative for bronchia...
متن کاملTesting bronchial hyper-responsiveness: provocation or peak expiratory flow variability?
BACKGROUND Assessing bronchial hyper-responsiveness (BHR) is a main diagnostic criterion of asthma. Provocation testing is not readily available in general practice, but peak expiratory flow (PEF) is. Several guidelines promote the use of PEF variability as a diagnostic tool for BHR. This study tested the agreement between histamine challenge testing and PEF variability, and the consequences fo...
متن کاملMethacoline Challenge test as an Evaluator of Response to Statins in Bronchial Hyperresponsiveness
3-hydroxy-3-methylglutaryl-CoA reductase inhibitors (statins), are effective serum cholesterol-lowering agents which also have anti-inflammatory properties. The objective of this study was to evaluate the effect of atorvastatin on bronchial hyperresponsiveness. Adult patients (age 14 to 65 years) with bronchial hyperresponsiveness (BHR) diagnosis based on the spirometry with methacholine challe...
متن کاملComparison of bronchial challenge with ultrasonic nebulized distilled water and hypertonic saline in children with mild-to-moderate asthma.
There is still controversy about the most suitable method to measure bronchial hyperresponsiveness in children. In epidemiological surveys, nonisotonic aerosols are being used increasingly for bronchial provocation testing. Our aim was to study the acceptability, safety and correlation between two published bronchial challenge tests. Two standardized protocols--the inhalation of hypertonic sali...
متن کامل