A new saponin from the leaves and stems of Panax quinquefolium L. collected in Canada.
نویسندگان
چکیده
A new dammarane-type saponin named quinquenoside L3 (1) together with vina-ginsenoside R3 (2) were isolated from the leaves and stems of Panax quinquefolium L. collected in Canada. On the basis of physicochemical and spectral evidences, 1 was established as 3-O-beta-D-glucopyranosyl-20-O-[beta-D-xylopyranosyl-(1-->6)-beta-D -glucopyranosyl] 20(S)-dammar-23-ene-3 beta, 12 beta,20,25-tetryol.
منابع مشابه
Quality Assessment and Ecotype Distinction for Panax quinquefolius L. from China and Canada by H NMR and Chemometrics
Article history: Received on: 09/11/2016 Accepted on: 07/01/2017 Available online: 30/05/2017 Panax quinquefolius L. is one of the most widely consumed and cultivated herbal medicines around the world. China and Canada are the two major producing countries. However, research on the ecotype distinction of P. quinquefolius from Canada has never been reported, and the quality evaluation of P. quin...
متن کاملPanax quinquefolium saponin attenuates cardiomyocyte apoptosis induced by thapsigargin through inhibition of endoplasmic reticulum stress
BACKGROUND Endoplasmic reticulum (ER) stress-related apoptosis is involved in the pathophysiology of many cardiovascular diseases, and Panax quinquefolium saponin (PQS) is able to inhibit excessive ER stress-related apoptosis of cardiomyocytes following hypoxia/reoxygenation and myocardial infarction. However, the pathway by which PQS inhibits the ER stress-related apoptosis is not well underst...
متن کاملStudies on the Adaptogenic and Antibacterial Properties of Polyscias Fructicosa (l) Harms
In the present study the adaptogenic activities of the saponin fractions of the leaves and roots of Polyscias fruticosa (L) Harms (Araliaceae) were studied in comparision wit white panax ginseng root saponins. The antibacterial activity of the polyacetylenic compound in leaves were also studied. The adaptogenic activity studies showed that polyscias fruticosa leaf and root saponins have effecti...
متن کاملPanax quinquefolium saponin attenuates cardiomyocyte apoptosis and opening of the mitochondrial permeability transition pore in a rat model of ischemia/reperfusion.
AIMS Opening of the mitochondrial permeability transition pore (mPTP) is a critical event during ischemia/reperfusion (I/R) injury. Recently, we showed that Panax quinquefolium saponin (PQS) alleviates apoptosis of cardiomyocytes by suppressing excessive endoplasmic reticulum stress (ERS) during I/R injury. Here, we hypothesized that this anti-apoptotic effect might be mediated through inhibiti...
متن کامل(3R,6R,12R,20S,24S)-20,24-Epoxydammarane-3,6,12,25-tetraol dihydrate
The title compound, C(30)H(52)O(5)·2H(2)O, was degraded from pseudoginsenoside F11 which was extracted and seperated from Panax quinquefolium saponin. The three six-membered rings are in chair conformations. The five-membered ring is in an envelope conformation and the tetra-hydro-furan ring has a conformation inter-mediate between half-chair and envelope. In the crystal, inter-molecular O-H⋯O ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of Asian natural products research
دوره 1 2 شماره
صفحات -
تاریخ انتشار 1998