Probiotics for Preterm Infants - The Story Searching for an End.
نویسنده
چکیده
Advances in neonatal intensive care have increased the survival rates of extremely preterm infants. Necrotizing enterocolitis (NEC), late onset sepsis (LOS) and suboptimal nutrition raise the risk of death and long-term neurodevelopmental impairment (NDI) in this population. Improving survival without long-term NDI in extremely preterm infants is a priority. Interventions that optimize enteral nutrition while decreasing the risk of NEC and LOS are therefore urgently needed for preterms, especially extremely preterm infants.
منابع مشابه
Prophylactic Probiotics for Preterm Infants: A Systematic Review and Meta-Analysis of Observational Studies
Background: Necrotizing enterocolitis (NEC) is a major morbidity and cause of mortality in preterm neonates. Probiotics seem to have a beneficial role in preventing NEC, which is confirmed in meta-analyses of randomized controlled trials (RCTs). We therefore aimed to review and confirm the efficacy of probiotics in preterm neonates obtained in observational studies. Objective: To assess the eff...
متن کاملProphylactic Probiotics for Preterm Infants: A Systematic Review and Meta-Analysis of Observational Studies.
BACKGROUND Necrotizing enterocolitis (NEC) is a major morbidity and cause of mortality in preterm neonates. Probiotics seem to have a beneficial role in preventing NEC, which is confirmed in meta-analyses of randomized controlled trials (RCTs). We therefore aimed to review and confirm the efficacy of probiotics in preterm neonates obtained in observational studies. OBJECTIVE To assess the eff...
متن کاملThe Effect of Probiotics on Late-Onset Sepsis in Very Preterm Infants: A Randomized Clinical Trial
Background Late onset sepsis is a frequent complication of prematurity, associated with increased mortality and morbidity. Probiotics may prevent late onset sepsis in premature infants. The aim of this study was to determine prophylactic effect of oral probiotics in prevention of late onset sepsis of very preterm infants. Materials and Methods This study was a randomized, double blinded, placeb...
متن کاملProphylactic Probiotics for Preterm Infants: A Systematic Review and Meta-Analysis of Observational Studies
Background: Necrotizing enterocolitis (NEC) is a major morbidity and cause of mortality in preterm neonates. Probiotics seem to have a beneficial role in preventing NEC, which is confirmed in meta-analyses of randomized controlled trials (RCTs). We therefore aimed to review and confirm the efficacy of probiotics in preterm neonates obtained in observational studies. Objective: To assess the eff...
متن کاملProbiotics and Prebiotics: Role in Prevention of Nosocomial Sepsis in Preterm Infants
Nosocomial sepsis is associated with increased mortality and morbidity including neurodevelopmental impairment and prolonged hospital stay. Prevention of sepsis especially in the preterm infants in the neonatal intensive care unit remains a major challenge. The gastrointestinal tract is an important source of potential pathogens causing nosocomial sepsis as the immature intestinal epithelium ca...
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ورودعنوان ژورنال:
- Indian pediatrics
دوره 54 5 شماره
صفحات -
تاریخ انتشار 2017