A New Bezoxepine Derivative from Senecio desfontainei

نویسندگان

  • Syed Hamid Hussain
  • Abdul Latif
  • Mohammad Arfan
  • Mumtaz Ali
  • Thomos J Simpson
  • Russell J Cox
  • Farzana Shaheen
  • Ghias Uddin
چکیده

Phytochemical investigation of the aerial parts of Senecio desfontainei afforded one new benzoxepine derivative, senecioside (1) along with eleven known compounds (2-12). Their structures were assigned from H and C NMR spectra, DEPT and 2D COSY, NOE, HSQC and HMBC NMR experiments. All these compounds were tested for antioxidant activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay. Among them, compounds 2, 3, 4, 6 and 9 showed significant antioxidant activity against DPPH radicals.

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تاریخ انتشار 2013