One pot synthesis of selenocysteine containing peptoid libraries by Ugi multicomponent reactions in water.

نویسندگان

  • Muhammad Abbas
  • John Bethke
  • Ludger A Wessjohann
چکیده

Selenocysteine containing peptoids and peptide-peptoid conjugates were synthesized by combinatorial Ugi-MCRs (multicomponent reactions) in water: for the first time, an acetal (selenoacetal 2a) was used in Ugi-MCR to furnish selenocysteine peptoids in one step as model compounds for selenocysteine peptides and proteins.

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عنوان ژورنال:
  • Chemical communications

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2006