Use of Tolterodine extended Release in Overactive Bladder
نویسنده
چکیده
Overactive bladder (OAB) is a common problem whose prevalence increases with advancing age and compromises health-relatedqualityoflife.TolterodinewasthefirstantimuscarinicdrugspecificallydesignedtotreatOAB. ThroughMEDLINE,wereviewedarticles,standardizationreportsandmeetingabstracts,publishedbetween2001and2011,ontheefficacy and tolerability of Tolterodine extended release (ER). Our search terms included Tolterodine, extended release, overactive bladder, therapeuticuse,efficacy,tolerance,andadverseevents. TolterodineER,viasteadydrugreleaseduringthedaytime,givesthebenefitofconstantserumconcentrationandthusbetterefficacy and tolerability in comparison to Tolterodine immediate release, even in elderly patients with co-morbid conditions.
منابع مشابه
The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly
After lifestyle and behavioral measures to control overactive bladder, the mainstay of pharmacological treatment is the use of antimuscarinic therapy. Overactive bladder predominantly affects older people, who experience the most severe disease, and are also at a greater risk of side effects from antimuscarinic therapy. Thus it is imperative that data are available on the efficacy and tolerabil...
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Overactive bladder is a prevalent condition which negatively impacts quality of life and puts a significant economical burden on society. First-line therapy often includes pharmacotherapy with antimuscarinic medications, and numerous research studies have demonstrated that tolterodine extended-release (ER) is an efficacious and tolerable formulation of this class of medication. This review prov...
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