Heparin-induced thrombocytopenia in the cardiovascular patient: diagnostic and treatment guidelines.
نویسندگان
چکیده
Heparin-induced thrombocytopenia/thrombosis is an immunologic reaction to unfractionated heparin characterized by thrombocytopenia, platelet activation and thrombosis. A high index of suspicion is required for timely diagnosis and treatment. Treatment is complex and outcome maybe less then satisfactory.
منابع مشابه
Heparin induced thrombocytopenia
Abstract Background and Objectives Heparin is still a commonly used anticoagulant in prophylaxis and treatment of thromboembolic events. Heparin-induced thrombocytopenia (HIT) is a life-threating adverse drug reaction of heparin. The diagnosis of HIT is made based on two important criteria, firstly clinical evaluation and secondly laboratory testing. In this comprehensive review, the authors w...
متن کاملبروز ترومبوسیتوپنی ناشی ازهپارین، در دو روش تجویز داخل وریدی در بیماران با سندرم حاد کرونری
Incidence of Thrombocytopenia Induced by Two Methods of Intravenous Heparin injection in Patients with Acute Coronary Syndrome. H. Nough MD1* , A. Khodadadi Zadeh MSc2, M. Aref 3, A. Esmaieli Nadimi MD1 1- Assisstant Professor of Cardiology, University of Medical Sciences, Rafsanjan, Iran 2- Academic Member, Dept. of Nursing, Faculty of Nursing Midwifery, University of Medical Sci...
متن کامل[Croatian Society for Haematology and Transfusion Medicine Guidelines on the diagnosis and management of heparin induced thrombocytopenia (HIT)].
Heparin induced thrombocytopenia (HIT) is a serious complication of heparin administration. In the last decade, this clinical syndrome has come into the focus of interest, primarily because of the severe thromboembolic complications that may lead to lethal outcome. In addition, great improvements have been made in the treatment with direct thrombin inhibitors and in laboratory diagnosis of HIT....
متن کاملA case of heparin-induced thrombocytopenia with repeated episodes of acute lower extremity arterial thromboembolism during a short time.
The patient was a 55-year-old female. On the diagnosis of the right acoustic tumor, a subtotal extirpation was performed. Heparinized solution was administered, and on postoperative day 7, an occlusion of the left common femoral artery was confirmed. A continuous administration of heparin was initiated after a thrombectomy. On the following day, the platelet count decreased. Following confirmat...
متن کاملA diagnostic test for heparin-induced thrombocytopenia.
Heparin-induced thrombocytopenia can be a serious and difficult-to-diagnose complication of heparin therapy. Serum from patients with heparin-induced thrombocytopenia can cause heparin-dependent platelet aggregation, but the low sensitivity and specificity of this test limit its clinical usefulness. In this report we describe an assay for heparin-induced thrombocytopenia that is both sensitive ...
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ورودعنوان ژورنال:
- European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
دوره 27 1 شماره
صفحات -
تاریخ انتشار 2005