Improved navigator based diffusion tensor MRI of the human heart in vivo

نویسندگان

  • PF Ferreira
  • S Nielles-Vallespin
  • PD Gatehouse
  • R de Silva
  • J Keegan
  • P Speier
  • T Feiweier
  • TG Reese
  • TF Ismail
  • A Scott
  • C Mekkaoui
  • DE Sosnovik
  • D Firmin
چکیده

Background In vivo Cardiac Diffusion Tensor Imaging (cDTI) remains extremely challenging due to a mixture of cardiac and respiratory motion. In previous work a prospective navigator technique (NAV) has been implemented and compared to breath-hold (BH) acquisitions. Statistically significant differences were found between BH and NAV techniques for helix-angle (HA) values. Further interrogation of the data suggested that the inconsistent HA patterns were found in NAV data sets in which a small fraction (up to 10%) of the diffusion-weighted frames had signal voids in some part of the LV. The purpose of this work was to improve the robustness of the NAV technique.

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عنوان ژورنال:

دوره 15  شماره 

صفحات  -

تاریخ انتشار 2013