Psychophysiological prediction of substance abuse.

A decade of large-scale, cross-sectional, and longitudinal research on adolescents has provided a wealth of information concerning the personality and psychosocial correlates of adolescent drug abuse. However, relatively little is known about psychophysiological factors related to drug abuse. This chapter outlines a rationale for the psycho-physiological investigation of psychoactive substance use disorders and introduces several experimental paradigms likely to identify psycho-physiological characteristics underlying the vulnerability for substance abuse (SA).