Concerning the Wassermann Reaction
نویسنده
چکیده
Sir,?In the December 1943 issue of the Indian Medical Gazette under the article on ' Concerning the ?Wassermann Reaction' I fail to see why smallpox vaccination as one of the causes producing false positive reactions has not been mentioned. Hence will you please publish the following in your valuable monthly :? False positive syphilitic reactions have been attributed to numerous causes, with smallpox vaccination recently added to the list. Using the Kolmer, Kline, Kinton and Mazzini techniques, Lynch found that pseudo-syphilitic serum reactions developed in 16 per cent of his patients within two weeks after vaccination. The serum usually remained positive for at least two months (Journal of American Medical Association, 117, 591, 23rd August, 1941). In order to confirm these data, a group of 202 serologically negative medical students and nurses was vaccinated by favour of Hahnemann Medical College followed by periodic serologic tests with the Kolmer, Kalin and Mazzini techniques. From 14 to 60 days after vaccination 24 of these (11.8 per cent) gave positive pseudo-syphilitic reactions; many of the reactions were of 3 or 4 plus intensity. All sehun became negative by the end of
منابع مشابه
Preliminary evaluation of the treponemal Wassermann reaction (T.W.R.).
Most of the relatively few papers on the treponemal complement-fixation reaction give good reports of this test. Thus, for example, Garson and Portnoy (1957) report that the treponemal complement-fixation test gives good reproducibility, is at least as sensitive in early syphilis as the conventional reagin tests, and has a greater value in confirming a diagnosis of early syphilis than the trepo...
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The subject of Wassermann "Problem" cases is of interest not only to the serologist but to the physician or clinician, upon whom devolves the responsibility for diagnosis. In the past there has been too little critical judgment by clinicians in assessing the results of the Wassermann reaction, and many practitioners may still regard a positive Wassermann reaction as in itself a diagnosis of syp...
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The Wassermann reaction in scarlet fever per se is uniformly negative. The antigen of scarlet fever liver yields practically the same results as that of luetic liver, and both fail to deviate complement with scarlet fever antibodies. The Noguchi reaction in scarlet fever is practically negative. Sixteen cases, or 6.4 per cent. of 250 cases, were positive when active serum was used; with inactiv...
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