Antioxidant,Antiinflammatory and Antifungal Activity of Marine Sponge Subergargoria suberosa-Derived Natural Products
نویسنده
چکیده
Chemical examination of the ethanol extract of the Indian ocean gorgonian coral Subergorgia suberosa resulted in isolation and identification of revealed compound 1 to be subergorgic acid 1 and a two bio-active analogues 2 and 7 were synthesized by the NaBH4 reduction of compound 1. The present investigation aimed to carry out invitro understanding the antioxidant,anti-inflammatory and antifungal activities for understanding immunostimulatory properties subergorgic acid 1 and its two analogues compound 2 and compound7.
منابع مشابه
Biological Activity of Recently Discovered Halogenated Marine Natural Products
This review presents the biological activity-antibacterial, antifungal, anti-parasitic, antiviral, antitumor, antiinflammatory, antioxidant, and enzymatic activity-of halogenated marine natural products discovered in the past five years. Newly discovered examples that do not report biological activity are not included.
متن کاملAntimicrobial activities of semi polar-nonpolar and polar secondary metabolites of sponge Dysidea pallescens from Hengam Island, Persian Gulf
Sponges are the simplest multicellular animals that lack defense mechanisms and rely on chemical defense that have been used by mankind to develop antimicrobial drugs against diseases. The present study was designed to demonstrate the antibacterial and antifungal activities of marine sponge Dysidea pallescens semipolar and nonpolar extracts. In this study, D. pallescens were collected from He...
متن کاملNeosiphoniamolide A, a novel cyclodepsipeptide, with antifungal activity from the marine sponge Neosiphonia superstes.
A novel cyclodepsipeptide, neosiphoniamolide A [1], has been isolated from the sponge Neosiphonia superstes. The structure of 1, which contains a 12-carbon hydroxy acid, glycine, valine, and a halogenated tyrosine residue in an 18-membered ring, is related to jaspamide and the geodiamolides, previously isolated from sponges. The structure was solved by spectroscopic analysis.
متن کاملSulfated Steroid–Amino Acid Conjugates from the Irish Marine Sponge Polymastia boletiformis
Antifungal bioactivity-guided fractionation of the organic extract of the sponge Polymastia boletiformis, collected from the west coast of Ireland, led to the isolation of two new sulfated steroid-amino acid conjugates (1 and 2). Extensive 1D and 2D NMR analyses in combination with quantum mechanical calculations of the electronic circular dichroism (ECD) spectra, optical rotation, and 13C chem...
متن کاملA New Dibenz[b, e]oxepine Derivative, 1-Hydroxy-10-methoxy-dibenz[b, e]oxepin-6,11-dione, from a Marine-Derived Fungus, Beauveria bassiana TPU942
1-Hydroxy-10-methoxy-dibenz[b,e]oxepin-6,11-dione (1) was obtained from the culture broth of a marine-derived fungus, Beauveria bassiana TPU942, isolated from a marine sponge collected at Iriomote Island in Okinawa, together with two known compounds, chrysazin (2) and globosuxanthone A (3). The structure of 1 was elucidated on the basis of its spectroscopic data (HREIMS, 1D and 2D NMR experimen...
متن کامل