Combinatorial Approaches to Gene Recognition

نویسندگان

  • Mikhail A. Roytberg
  • Tatiana V. Astakhova
  • Mikhail S. Gelfand
چکیده

Recognition of genes via exon assembly approaches leads naturally to the use of dynamic programming. We consider the general graph-theoretical formulation of the exon assembly problem and analyze in detail some specific variants: multicriterial optimization in the case of non-linear gene-scoring functions; context-dependent schemes for scoring exons and related procedures for exon filtering; and highly specific recognition of arbitrary gene segments, oligonucleotide probes and polymerase chain reaction (PCR) primers.

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عنوان ژورنال:
  • Computers & chemistry

دوره 21 4  شماره 

صفحات  -

تاریخ انتشار 1997