A new class of antiemetic agents on the horizon.
نویسنده
چکیده
This article reviews a new class of antiemetic agents, the neurokinin-1 (NK-1) receptor antagonists (RAs). Clinical trials of an NK-1 RA, aprepitant, are ongoing.
منابع مشابه
Integrating aprepitant and palonosetron into clinical practice: a role for the new antiemetics.
Chemotherapy-induced nausea and vomiting (CINV) are among the most feared side effects of cancer treatment. With increasingly more complex chemotherapy treatments, CINV plays an important role in determining patients' quality of life, as well as when to halt potentially lifesaving therapy. Although significant progress has been made in the treatment of CINV, patients undergoing chemotherapy con...
متن کاملکنترل تهوع و استفراغ با دوز کم متوکلوپروماید در بیماران تحت شیمی درمانی
Nausea and vomiting have long been the most troublesome side effects of chemotherapy. This study was designed to evaluate the abinty of metoclopramide to control nausea and vomiting in a group of patients with lung non small cell carcinoma on CAP (Cyclophosphamide, Adriamycin and Cisplatin) chemotherapy protocol. 42 patients, 30 male and 12 female, ages from 40-70 years were entered in this stu...
متن کاملSolving infinite horizon optimal control problems of nonlinear interconnected large-scale dynamic systems via a Haar wavelet collocation scheme
We consider an approximation scheme using Haar wavelets for solving a class of infinite horizon optimal control problems (OCP's) of nonlinear interconnected large-scale dynamic systems. A computational method based on Haar wavelets in the time-domain is proposed for solving the optimal control problem. Haar wavelets integral operational matrix and direct collocation method are utilized to find ...
متن کاملA new switching strategy for exponential stabilization of uncertain discrete-time switched linear systems in guaranteed cost control problem
Uncertain switched linear systems are known as an important class of control systems. Performance of these systems is affected by uncertainties and its stabilization is a main concern of recent studies. Existing work on stabilization of these systems only provides asymptotical stabilization via designing switching strategy and state-feedback controller. In this paper, a new switching strate...
متن کاملDefining the emetogenicity of cancer chemotherapy regimens: relevance to clinical practice.
Significant progress has been made in recent years in developing more effective and better tolerated means to prevent nausea and vomiting induced by cancer chemotherapy. The most significant development has been the introduction of a new class of antiemetic agents, the selective antagonists of the type 3 serotonin receptor. With the new antiemetic therapeutic options and their attendant higher ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Clinical journal of oncology nursing
دوره 6 2 شماره
صفحات -
تاریخ انتشار 2002