The Adult of Microfilaria Malayi Brug, 1927
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چکیده
منابع مشابه
Moxidectin causes adult worm mortality of human lymphatic filarial parasite Brugia malayi in rodent models.
Moxidectin is a macrocyclic lactone belonging to milbemycin family closely related to ivermectin and is currently progressing towards Phase III clinical trial against human infection with the filaria Onchocerca volvulus (Leuckart, 1894). There is a single report on the microfilaricidal and embryostatic activity of moxidectin in case of the human lymphatic filarial parasite Brugia malayi (Brug, ...
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Glutamate-gated chloride channels (GluCl) are targets for avermectin/milbemycin (A/M) anthelmintics such as ivermectin that cause paralysis of somatic and pharyngeal muscles in gastrointestinal nematodes. Ivermectin is useful for onchocerciasis control programs because of its activity against microfilariae that often cause ocular disease and severe dermatitis. However, mechanisms responsible fo...
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The full-length cDNA sequence encoding Brugia malayi L3 paramyosin has been isolated by immunoscreening a cDNA library with a mouse antiserum raised against Wuchereria bancrofti L3 infective larvae. A recombinant truncated form of paramyosin was expressed as a glutathione S-transferase fusion protein and used to evaluate humoral responses of adults from a W. bancrofti-endemic area in French Pol...
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A tiny islet named Hachijo-Koshima was known as the only one focus of brugian filariasis in Japan. It is located about 300 km south to Tokyo in the Pacific Ocean. It had been rather hard to access due to the lack of the regular transportation system. The island was visited for the first time after the last World War II by the medical doctors for the investigation of the nature of a debilitating...
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