Tandem Michael addition/imine isomerization/intramolecular [3+2] cycloaddition for the regiospecific synthesis of cyclohepta[b]pyrroles.
نویسندگان
چکیده
The polarity reversible nature of azomethine imines as the crucial transformation enables the tandem Michael addition/imine isomerization/[3+2] cycloaddition to proceed under mild, transition-metal-free conditions to form cyclohepta[b]pyrroles in a single operation starting from readily available acyclic precursors with a broad substrate scope.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 75 شماره
صفحات -
تاریخ انتشار 2014