[the action of mebeverine on rabbit colon].
نویسندگان
چکیده
1. The spontaneous contraction of the isolated colon was inhibited by mebeverine at doses greater than 1•~10-7g/ml. The effect of mebeverine was stronger than that of papaverine or buscopan. Two kinds of movement occur in the rabbit colon, peristaltic movement and the local tonic wave. The local tonic wave is produced mainly by the ring muscle. Papaverine mainly inhibited the peristaltic contractions but the effect of mebeverine and that of buscopan were the inhibition of tonic contractions. These drugs showed greater inhibitory effects on the colonic activity than on the small intestinal one.
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ورودعنوان ژورنال:
- Nihon Heikatsukin Gakkai zasshi
دوره 4 1 شماره
صفحات -
تاریخ انتشار 1968