Primary mucosa-associated lymphoid tissue (MALT) lymphoma of the minor salivary glands in the upper and lower lips of a male paediatric patient

Mucosa-Associated Lymphoid Tissue (MALT) lymphoma also referred to as extranodal marginal zone B-cell lymphoma, is rare in the oral soft tissue [1-8]. Primary MALT lymphomas are most commonly seen in the gastrointestinal tract [1,2,4]. Within the oral soft tissue, the salivary glands are the most affected with the parotid gland being the most common site [9] and the minor salivary glands being the least common site [4]. MALT lymphomas of the lip are exceptionally uncommon with few reported cases in the literature [1-3,8,10]. Middle aged and older adults exhibit the high highest frequency of MALT lymphomas. Pediatric cases are exceedingly rare and are most often associated with immunocompromised patients [3-8,11]. A female predilection is seen in both the pediatric population [10] as well as in the adult population [4,6]. All the reported case of MALT lymphoma of the lip has been isolated to a single lip. This paper, to the best of our knowledge, is the first reported case of primary MALT lymphoma of both the upper and lower lips.