The genomic rate of adaptive evolution.

نویسنده

  • Adam Eyre-Walker
چکیده

The role of positive darwinian selection in evolution at the molecular level has been keenly debated for many years, with little resolution. However, a recent increase in DNA sequence data and the development of new methods of analysis have finally made this question tractable. Here, I review the current state-of-play of the field. Initial estimates in Drosophila suggest that approximately 50% of all amino acid substitutions, and a substantial fraction of substitutions in non-coding DNA, have been fixed as a consequence of adaptive evolution. Estimates in microorganisms are even higher. By contrast, there is little evidence of widespread adaptive evolution in our own species.

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عنوان ژورنال:
  • Trends in ecology & evolution

دوره 21 10  شماره 

صفحات  -

تاریخ انتشار 2006