Polycythemia of the newborn

نویسندگان

  • MARIA HAJDUCZENIA
  • OSKAR JAREMBA
  • MARTA SZYMANKIEWICZ
چکیده

Polycythemia is defined as a venous hematocrite above 65%. The relationship between viscosity and hematocrite is almost linear till 65% and exponential thereafter. The etiology of polycythemia is related either to intrauterine hypoxia or secondary to fetal transfusion. Most polycythaemic infants are asymptomatic. Increased viscosity of blood may be associated with symptoms of hypoperfusion. Clinical features related to polycythemia may affect all organ systems. Screening for polycythemia should be performed in certain high-risk groups. Partial exchange transfusion (PET) is accepted yet still controversial treatment of polycythemia. There is no clinically important difference between crystalloids and colloids in reducing hematocrite. Since crystalloids are more readily available and cheaper and do not confer any risk of infection or anaphylaxis, crystalloids are the optimal therapeutic fluid. PET is effective in reducing hematocrite and in relieving symptoms related to polycythemia. However, there is no reliable evidence of clinically important benefit from PET, especially of a long term neurological benefit.

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تاریخ انتشار 2010