Retrospective study of intellectual development in children treated for acute lymphoblastic leukaemia.
نویسندگان
چکیده
Nine younger children (mean age 6-3 years) and 6 older children (mean age 9-0 years), previously treated for acute lymphoblastic leukaemia by cranial irradiation and subsequently by 2 or 3 years of chemotherapy, were assessed in terms of intellectual development in relation to 15 controls, matched individually for age, sex, and social background. All children were functioning within a normal range. The older group of children performed as well as their matched controls in all tasks. However, the younger group tended to perform somewhat below their matched controls, and this applied especially to tasks measuring quantitative, memory, and motor skills, but not to language tasks. It is concluded that there is a continual need to monitor the development of children treated for leukaemia, especially when diagnosed in the 2- to 5- year age range.
منابع مشابه
Effects of chronic illness on intellectual development. A comparison of normal children with those treated for childhood leukaemia and solid tumours.
40 children who had been treated for acute lymphoblastic leukaemia by irradiation to the central nervous system and by chemotherapy were assessed, using general psychological measures. These children were compared with a group of normal children of similar ages and backgrounds, and with a group of 16 patients treated for solid tumours. The group of 16 patients with solid tumours was also compar...
متن کاملGene variants of CYP1A1 and CYP2D6 and the risk of childhood acute lymphoblastic leukaemia; outcome of a case control study from Kashmir, India
Studies on associations of various polymorphisms in xenobiotic metabolizing genes with different cancers including acute lymphoblastic leukaemia (ALL) are mixed and inconclusive. The current study analyzed the relationship between polymorphisms of phase I xenobiotic metabolizing enzymes, cytochromes P450 1A1 (CYP1A1) and CYP2D6 and childhood ALL in Kashmir, India. We recruited 200 confirmed ALL...
متن کاملDental Anomalies and Dental Age Assessment in Treated Children with Acute Lymphoblastic Leukemia
Background This cross sectional study was performed to evaluate dental ages and incidence of dental anomalies in children treated for acute lymphoblastic leukemia (ALL). Methods and materials A total of 25 ALL patient who passed at least 2 years of chemotherapy and 25 healthy sex and age matched children were evaluated. Dental age as well as dental anomalies in shape, size, number, and s...
متن کاملEffects of chronic illness on intellectual development
40 children who had been treated for acute lymphoblastic leukaemia by irradiation to the central nervous system and by chemotherapy were assessed, using general psychological measures. These children were compared with a group of normal children of similar ages and backgrounds, and with a group of 16 patients treated for solid tumours. The group of 16 patients with solid tumours was also compar...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 52 7 شماره
صفحات -
تاریخ انتشار 1977