On the nomenclature of complex carbohydrates.

نویسنده

  • C K Knospe
چکیده

Some histochemists still distinguish between “neutral and acid mucopolysaccharides” based on reactions such as the periodic acid-Schiff (PAS) and Alcian blue staining. In the same way terms such as “neutral and acid glycoconjugates” are used. Apart from the fact that the so-called acid mucopolysaccharides can also give a positive PAS-reaction, this classification does not reflect the real nature of these substances. This classification is also in conflict with the nomenclature of biochemists and gives no impression of the chemical composition of these substances. To be fair, it must be remarked that biochemists are also inconsistent in their terminology. Today we have special techniques that can detect the main sugar, the functional groups, and in some cases, the linkage, so that the term “acid and neutral mucopolysaccharides” should no longer be used. As long as the precise structure of the histochemically demonstrated proteoglycans is unknown, the terms glycoglycans (for polysaccharides with hexoses), glycosaminoglycans (for aminosugars-contaming polysaccarides), and fucoglycans and sialoglycans (for fucoseand sialin acid-containing polysaccharides) can be used. Important substituents should be accommodated by using such terms as phospho-, acetyland sulfoglycans (or sulphoglycans). I would like to recommend that a commission be formed to work out an agreement between histochemists, biochemists and carbohydrate chemists on the acceptance of a uniform nomenclature in all three specialized branches of science.

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عنوان ژورنال:
  • The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

دوره 32 4  شماره 

صفحات  -

تاریخ انتشار 1984