Crystal Structure of the Mobile Metallo - β - 1 Lactamase AIM - 1 from Pseudomonas aeruginosa : 2 Insights into Antibiotic Binding and the role of 3 Gln 157 4

نویسندگان

  • Hanna-Kirsti S. Leiros
  • Pardha S Borra
  • Bjørn Olav Brandsdal
  • James Spencer
  • Timothy R. Walsh
  • Ørjan Samuelsen
چکیده

Running title (max 54 characters including space): 25 Structure of the mobile B3 MBL: AIM-1 26 27

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BACKGROUND Metallo-β-lactamase-production among Gram-negative bacteria, including Pseudomonas aeruginosa, has become a challenge for treatment of infections due to these resistant bacteria. OBJECTIVES The aim of the current study was to evaluate the metallo-β-lactamase-production and carriage of bla-VIM genes among carbapenem-resistant P. aeruginosa isolated from burn wound infections. PATI...

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تاریخ انتشار 2012