Iberiotoxin-induced Block of KCa Channels Induces Dihydropyridine Sensitivity of ACh Release from Mammalian Motor Nerve Terminals
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Iberiotoxin-Induced Block of Ca -Activated K Channels Induces Dihydropyridine Sensitivity of ACh Release from Mammalian Motor Nerve Terminals
The role which Ca -activated K (KCa) channels play in regulating acetylcholine (ACh) release was examined at mouse motor nerve terminals. In particular, the ability of the antagonist iberiotoxin to recruit normally silent L-type Ca channels to participate in nerve-evoked release was examined using conventional intracellular electrophysiological techniques. Incubation of cut hemidiaphragm prepar...
متن کاملIberiotoxin-induced block of Ca2+-activated K+ channels induces dihydropyridine sensitivity of ACh release from mammalian motor nerve terminals.
The role which Ca(2+)-activated K(+) (K(Ca)) channels play in regulating acetylcholine (ACh) release was examined at mouse motor nerve terminals. In particular, the ability of the antagonist iberiotoxin to recruit normally silent L-type Ca(2+) channels to participate in nerve-evoked release was examined using conventional intracellular electrophysiological techniques. Incubation of cut hemidiap...
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