Carriage of an ACME II variant may have contributed to methicillin-resistant Staphylococcus aureus sequence type 239-like strain replacement in Liverpool Hospital, Sydney, Australia.

نویسندگان

  • B A Espedido
  • J A Steen
  • T Barbagiannakos
  • J Mercer
  • D L Paterson
  • S M Grimmond
  • M A Cooper
  • I B Gosbell
  • S J van Hal
  • S O Jensen
چکیده

Approximately 39% of methicillin-resistant Staphylococcus aureus (MRSA) sequence type 239 (ST239)-like bloodstream isolates from Liverpool Hospital (obtained between 1997 and 2008) carry an arginine catabolic mobile element (ACME). Whole-genome sequencing revealed that an ACME II variant is located between orfX and SCCmec III, and based on pulsed-field gel electrophoresis patterns and temporal relationships of all ST239-like isolates (n = 360), ACME carriage may have contributed to subpulsotype strain replacement.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 56 6  شماره 

صفحات  -

تاریخ انتشار 2012