Bullous mycosis fungoides associated with an extensive ulcer and a severe leukemoid reaction
نویسندگان
چکیده
This report presents a case of bullous mycosis fungoides associated with an extensive ulcer and a severe leukemoid reaction. The rash began as indurated erythema which was always followed by ulceration. The rashes initially responded to radiation therapy, but multiple recurrences appeared. Several bullae appeared on the trunk during the course of the illness, without any evidence of paraneoplastic pemphigus. Finally, the ulcer covered a large part of the trunk, and the patient died of sepsis with an extreme leukocyte count of 118,000/µL. A bone marrow analysis revealed a leukemoid reaction and an autopsy revealed pseudomembranous colitis.
منابع مشابه
Report of a rare case of bullous mycosis fungoides
Mycosis fungicides (MF), on extremely rare occasions, can be associated with vesiculobullous eruptions. We describe a 74-year-old man with previous documented histopathologic diagnosis of poikilodermic type of MF who recently developed some flaccid acral bullae on erythemoatous MF plaque and normal skin. Histopathology and direct immunoflourscence studies revealed extensive lichenoid chan...
متن کاملBullous mycosis fungoides: report of a case
Mycosis fungoides is a common form of cutaneous T-cell lymphoma, with characteristic histopathology and chronic clinical course. Vesiculobullous mycosis fungoides is a rare occurrence. Here we present a 55-year-old man with multiple bullous plaques of one year duration who was finally diagnosed as a case of mycosis fungoides.
متن کاملReporting of drug eruptions: the National Pharmacovigilance Program.
In the daily drudgery of clinical practice, every now and then we come across a patient who is sure that a particular drug is affecting his or her skin in a peculiar way. However, to our brains, trained to recognize common drug eruptions, it seems fantastic that any drug could cause side effects such as digitate dermatosis, [1] mycosis fungoides, [2] leukemoid reaction, [3] leg ulcer [4] or eve...
متن کاملBullous Erythrodermic Mycosis Fungoides: A Case Report
Bullous mycosis fungoides is a rare entity of cutaneous T-cell lymphomas; however, it can be particularly aggressive with an unfavorable prognosis. Mechanism of formation of bullous lesions in bullous lymphoma remains poorly understood, it can be explained by excessive epidermotropism or tumor infiltration’s toxicity. We report the case of a bullous erythrodermic mycosis fungoides.
متن کاملMycosis fungoides with an unusual clinicopathological presentation
It is a challenging task to diagnose mycosis fungoides (MF), a type of primary cutaneous lymphoma, in the early stages of its development, due to the unspecific presentations associated with the disease. Histopathology and immunohistochemistry conduce to a more definite diagnosis. Presence of atypical T-cells in epidermis and upper dermis is the most significant pathologic finding. Herein...
متن کامل