CALL FOR PAPERS Translational Research in Acute Lung Injury and Pulmonary Fibrosis Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1
نویسندگان
چکیده
Masakazu Shinohara,* Megumi Kibi,* Ian R. Riley, Nan Chiang, Jesmond Dalli, Bryan D. Kraft, Claude A. Piantadosi, Augustine M. K. Choi, and Charles N. Serhan Center for Experimental Therapeutics and Reperfusion Injury, Harvard Institutes of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts; Department of Medicine, Duke University Medical Center, Durham, North Carolina; Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts; Division of Pulmonary and Critical Care Medicine, Weill Department of Medicine, Weill Cornell Medical College, New York, New York
منابع مشابه
Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1.
Polymorphonuclear leukocyte (PMN)-mediated acute lung injury from ischemia/reperfusion (I/R) remains a major cause of morbidity and mortality in critical care medicine. Here, we report that inhaled low-dose carbon monoxide (CO) and intravenous resolvin D1 (RvD1) in mice each reduced PMN-mediated acute lung injury from I/R. Inhaled CO (125-250 ppm) and RvD1 (250-500 ng) each reduced PMN lung inf...
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Orr SK, Colas RA, Dalli J, Chiang N, Serhan CN. Proresolving actions of a new resolvin D1 analog mimetic qualifies as an immunoresolvent. Am J Physiol Lung Cell Mol Physiol 308: L904–L911, 2015. First published March 13, 2015; doi:10.1152/ajplung.00370.2014.—Resolution of inflammation is an active process driven by several new families of endogenous lipid mediators collectively coined specializ...
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