N-(Prop-2-yn-1-yl)-1,3-benzothiazol-2-amine
نویسندگان
چکیده
In the title compound, C(10)H(8)N(2)S, the 2-amino-benzothia-zole and propyne groups are not coplanar [dihedral angle = 71.51 (1)°]. The crystal structure is stabilized by strong inter-molecular N-H⋯N hydrogen bonds and C-H⋯C, C-H⋯π and F-type aromatic-aromatic [centroid-centroid distance = 3.7826 (12) Å] inter-actions are also observed.
منابع مشابه
N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a new cholinesterase and monoamine oxidase dual inhibitor.
On the basis of N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine (II, ASS234) and QSAR predictions, in this work we have designed, synthesized, and evaluated a number of new indole derivatives from which we have identified N-methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine (2, MBA236) as ...
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In the title compound, C21H12N2O3, the fused-ring system is roughly planar, the largest deviation from the mean plane being 0.084 (2) Å. The two prop-2-yn-1-yl groups are almost perpendicular to the fused ring plane, making C-C-N-C torsion angles of -103.4 (2) and -105.3 (2)°, and point in opposite directions with respect to the plane. In the crystal, mol-ecules are linked by weak C-H⋯O hydroge...
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The mol-ecule of the title compound, C18H13NOS, is build up from two fused six-membered rings, with the heterocyclic component linked to a benzyl-idene group and to a prop-2-yn-1-yl chain. The six-membered heterocycle adopts a distorted screw-boat conformation. The prop-2-yn-1-yl chain is almost perpendicular to the mean plane through benzo-thia-zine as indicated by the C-N-C-C torsion angle of...
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The title complex, [Cd(C(6)H(17)N(3))(2)](ClO(4))(NO(3)), was synthesized by the reaction of Cd(NO(3))(2)·4H(2)O, bis-(3-amino-prop-yl)-amine and sodium perchlorate in methanol. The asymmetric unit of the title complex consists of one Cd(2+) cation, two tridentate bis-(3-amino-prop-yl)amine ligands, one nitrate anion and one perchlorate anion. The Cd(2+) cation is coordinated by six N atoms of ...
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In the title compound, C(13)H(12)N(4)S, an amino N atom is connected to a 1,3-benzothia-zole fused-ring system and a dimethyl-substituted pyrimidine ring, these components being aligned [inter-planar dihedral angle = 1.9 (1)°]. The secondary amino N atom forms an inter-molecular N-H⋯N hydrogen bond to an N atom of the fused ring of an adjacent mol-ecule, generating a centrosymmetric cyclic hydr...
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