Unique features of a global human ectoparasite identified through sequencing of the bed bug genome.
نویسندگان
چکیده
The bed bug, Cimex lectularius, has re-established itself as a ubiquitous human ectoparasite throughout much of the world during the past two decades. This global resurgence is likely linked to increased international travel and commerce in addition to widespread insecticide resistance. Analyses of the C. lectularius sequenced genome (650 Mb) and 14,220 predicted protein-coding genes provide a comprehensive representation of genes that are linked to traumatic insemination, a reduced chemosensory repertoire of genes related to obligate hematophagy, host-symbiont interactions, and several mechanisms of insecticide resistance. In addition, we document the presence of multiple putative lateral gene transfer events. Genome sequencing and annotation establish a solid foundation for future research on mechanisms of insecticide resistance, human-bed bug and symbiont-bed bug associations, and unique features of bed bug biology that contribute to the unprecedented success of C. lectularius as a human ectoparasite.
منابع مشابه
Bed bug bite, as an important health and urban pest
Bed bug (Cimex lectularius) is an nocturnal insect that feeding on human blood at all stages of them life, and known as a human ectoparasite. Bed bug is usually feeding from the face, neck, arms, arms, shoulders, legs, and especially parts of the body that are bare during sleep. Persons reaction differently to bed bug bites and may experience minor itching to severe allergies. Symptoms usually ...
متن کاملDetection and Characterization of Weissellicin 110, a Bacteriocin Produced by Weissella cibaria
Background: Weissellicin 110 is the only bacteriocin reported in Weissella cibaria up to now. This bacteriocin represents several unique features. This is the first report on the gene sequence that encodes for the bacteriocin. Objectives: Providing a rapid detection method to isolate the weissellicin 110 encoding gene and determination of the bacteriocin distribution were the objectives. Materi...
متن کاملBed bugs evolved unique adaptive strategy to resist pyrethroid insecticides
Recent advances in genomic and post-genomic technologies have facilitated a genome-wide analysis of the insecticide resistance-associated genes in insects. Through bed bug, Cimex lectularius transcriptome analysis, we identified 14 molecular markers associated with pyrethroid resistance. Our studies revealed that most of the resistance-associated genes functioning in diverse mechanisms are expr...
متن کاملBed bug (Cimex lectularis) outbreak: A cross-sectional study in Polour, Iran
Background: Cimex lectularius (bed bug) are insects abundantly found in hot, temperate areas. This study is related to the outbreak of Cimex lectularius in a construction site around Polour in Amol, Iran. This cross-sectional study has examined 182 prefabricated houses made of intermodal containers [Conex] converted to a temporary housing, in a construction site.Methods...
متن کاملHuman Odorant Reception in the Common Bed Bug, Cimex lectularius
The common bed bug Cimex lectularius is a temporary ectoparasite on humans and currently resurgent in many developed countries. The ability of bed bugs to detect human odorants in the environment is critical for their host-seeking behavior. This study deciphered the chemical basis of host detection by investigating the neuronal response of olfactory sensilla to 104 human odorants using single s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Nature communications
دوره 7 شماره
صفحات -
تاریخ انتشار 2016