Singlet Oxygen Trapping Porphyrins
نویسندگان
چکیده
منابع مشابه
Superoxide formation by protoporphyrin as seen by spin trapping.
The cutaneous photosensitivity of individuals with erythropoietic protoporphyria has been associated with the abnormally large amounts of protoporphyrin, found in the red blood cells [ 11. Patients with erythropoietic protoporphyria are sensitive to radiation near 400 nm which corresponds with the absorption maxima of protoporphyrin [2]. The photochemical damage is thought to be the result of l...
متن کاملSynthesis, singlet oxygen photogeneration and DNA photocleavage of porphyrins with nitrogen heterocycle tails.
Eight novel compounds were prepared by reaction of 5-(bromo- propoxyphenyl)-10,15,20-triphenylporphyrin with oxazole thiols, 1,3,4-oxadiazole thiols and 1,3,4-thiadiazole thiols, and their structures confirmed by UV-vis, IR, 1H-NMR, MS and elemental analysis. The assessment of indirectly measured 1O(2) production rates against 5,10,15,20-tetraphenyl porphyrin (H(2)TPP) were described and the re...
متن کاملCorrelation of photophysical parameters with macrocycle distortion in porphyrins with graded degree of saddle distortion.
Different porphyrin conformations are believed to play a role in controlling the cofactor properties in natural tetrapyrrole-protein complexes. In order to study the correlation between macrocycle nonplanarity and physicochemical properties in detail, a series of six porphyrins with graded degree of macrocycle distortion was investigated. These conformationally designed porphyrins are based on ...
متن کاملA multifunctional nanoassembly of mesogen-bearing amphiphiles and porphyrins for the simultaneous photodelivery of nitric oxide and singlet oxygen.
We report a molecular nanoassembly able to supply simultaneously, in the same region of space and under the exclusive control of visible light, nitric oxide and singlet oxygen, two species playing a key role in the therapy of cancer; the considerable fluorescence of this nanoaggregate and its reduced size (ca. 40 nm) represent additional advantages that make this photoactive vehicle an appealin...
متن کاملPhoton energy upconversion in porphyrins: one-photon hot-band absorption versus two-photon absorption
We study the porphyrin S1 ! S0 fluorescence and the photosensitized singlet oxygen Dg ! Rg phosphorescence, both originating from absorption of photons with energy less than the porphyrin S0 ! S1 transition energy. By measuring the excitation intensity dependence of fluorescence at lowered sample temperatures, we are able to discriminate between two parallel processes of one-photon hot-band abs...
متن کامل