Single-pass measurements of the wave-front aberrations of the human eye by use of retinal lipofuscin autofluorescence.
نویسندگان
چکیده
We describe a technique for making single-pass measurements of the wave-front aberration of the eye. The technique utilizes the natural fluorescence of the retina that is produced by lipofuscin to form an incoherent pointlike source for conventional Shack-Hartmann sensing.
منابع مشابه
Ocular aberrations with ray tracing and Shack-Hartmann wave-front sensors: does polarization play a role?
Ocular aberrations were measured in 71 eyes by using two reflectometric aberrometers, employing laser ray tracing (LRT) (60 eyes) and a Shack-Hartmann wave-front sensor (S-H) (11 eyes). In both techniques a point source is imaged on the retina (through different pupil positions in the LRT or a single position in the S-H). The aberrations are estimated by measuring the deviations of the retinal ...
متن کاملAberrations and retinal image quality of the normal human eye.
We have constructed a wave-front sensor to measure the irregular as well as the classical aberrations of the eye, providing a more complete description of the eye's aberrations than has previously been possible. We show that the wave-front sensor provides repeatable and accurate measurements of the eye's wave aberration. The modulation transfer function of the eye computed from the wave-front s...
متن کاملInvestigating the light absorption in a single pass through the photoreceptor layer by means of the lipofuscin fluorescence
Reflection densitometry has been widely used to measure the density difference of the bleachable cone photopigments in human eyes. Most such measurements make a series of assumptions concerning the amount of scattered light to derive an estimate of the true cone photopigment density from the density difference measurements. The current study made three types of measurements of the light returni...
متن کاملLaser Ray Tracing versus Hartmann-Shack sensor for measuring optical aberrations in the human eye.
A comparison and validation study of Laser Ray Tracing (LRT) and Hartmann-Shack wave-front-sensor (to be referred to as H-S) methods was carried out on both artificial and human eyes. The aim of this work was double. First, we wanted to verify experimentally the equivalence of single- and double-pass measurements for both H-S and LRT. This interest is due to the impossibility of making single-p...
متن کاملTemperature dependent fluorescence of A2-E, the main fluorescent lipofuscin component in the RPE.
PURPOSE A2-E is the dominant fluorophore of lipofuscin in the retinal pigment epithelium. In an in-vitro setup, we determined the temperature-dependent changes of the A2-E fluorescence with the aim of also assessing the potential value of such measurements for determining retinal temperature by autofluorescence measurements during laser treatment. METHODS A2-E was biosynthesized and diluted i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Optics letters
دوره 24 1 شماره
صفحات -
تاریخ انتشار 1999