Targeted gene replacement in Drosophila goes the distance.
نویسندگان
چکیده
In this commentary, K. Nicole Crown and Jeff Sekelsky examine new methods for gene targeting in Drosophila. These methods, which allow for rapid replacement of large regions adjacent to existing transgenic insertions, are described in two articles published in this month’s GENETICS: “Long-Range Targeted Manipulation of the Drosophila Genome by SiteSpecific Integration and Recombinational Resolution”; and “Captured Segment Exchange: A Strategy for Custom Engineering Large Genomic Regions in Drosophila melanogaster”.
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ورودعنوان ژورنال:
- Genetics
دوره 193 2 شماره
صفحات -
تاریخ انتشار 2013