Abstract: Injection Adipocytolysis with ATX-101 (Deoxycholic Acid) for Body Contouring
نویسندگان
چکیده
INTRODUCTION: Deoxycholic acid currently approved only for minimally invasive treatment of submental fat. The effects of deoxycholic acid on fat need not be limited to submental fat and represents an opportunity to treat undesired fat in many other body parts.1 Injection lipolysis has the potential risks of skin loss/necrosis, hyperpigmentation, neovascular response, and contour irregularities.2 There are no reports to date of results of body contouring using deoxycholic acid. This study shows the first real-world use of deoxycholic acid for non-submental locations for body contouring, and characterizes safety and efficacy of treatment.
منابع مشابه
Early Experience in 100 Consecutive Patients With Injection Adipocytolysis for Neck Contouring With ATX-101 (Deoxycholic Acid)
BACKGROUND Deoxycholic acid (DCA) is approved for improvement in the appearance of moderate to severe convexity or fullness associated with submental fat. OBJECTIVE To assess early treatment experience with DCA injection in a clinical practice setting. MATERIALS AND METHODS In this single-center, prospective, single-arm, observational study, 100 consecutive patients seeking to decrease subm...
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1. Kythera Biopharmaceuticals I. Dermatologic and ophthalmic drugs advisory committee briefing document: ATX-101 (deoxycholic acid) injection. https:// www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/DermatologicandOphthalmicDrugsAdvisoryCommittee/UCM436604.pdf. Accessed February 26, 2017. 2. Dayan SH, Humphrey S, Jones DH, et al. Overview of ATX-101 (Deoxycholic Acid ...
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1. Kythera Biopharmaceuticals I. Dermatologic and ophthalmic drugs advisory committee briefing document: ATX-101 (deoxycholic acid) injection. https:// www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/DermatologicandOphthalmicDrugsAdvisoryCommittee/UCM436604.pdf. Accessed February 26, 2017. 2. Dayan SH, Humphrey S, Jones DH, et al. Overview of ATX-101 (Deoxycholic Acid ...
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BAs: Bile acids DCA: deoxycholic acid FDA: Food and Drug Administration INTRODUCTION Bile acids (BAs) are endogenously produced cholesterol derivatives that are found predominantly in bile and play a key role in lipid digestion. The surfactant activity of BAs is responsible for fat emulsification and subsequent solubilization, a process that is requisite for intestinal lipid absorption. Deoxych...
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