Myocardial contrast two-dimensional echocardiography: a complement to coronary angiography.
نویسنده
چکیده
Rapid development of a new methodology is not altogether unusual in the current environment of diagnostic and interventional cardiology. Remarkable benefits might be projected, but scientists and clinicians alike must first develop an adequate understanding of the method's advantages and limitations . Myocardial contrast two-dimensional echocardiography represents a promising new diagnostic technique that has undergone extensive experimental validations as well as recent clinical trials . The preceding article in this issue of the Journal by Keller of al . (I) deals with an interesting application of contrast echocardiography and joins the growing literature in this field. Progress in contrast echocardiography . After early exploration (2,3), the Journal of the American College of Cardiology published in 1984 a seminar (4) featuring articles on echo contrast agents, assessment of ischemic risk zones and study of regional myocardial blood flow and function, by myocardial contrast echocardiography. Despite encouraging progress, the need was recognized to develop contrast agents as quantitative microcirculatory tracers, standardize intracoronary or alternate injections and enhance the echo image quality that underlies valid tissue contrast analysis . Significant recent developments include sonicated or other agents containing extremely small microbubbles (3 to 5 yam) to he uniformly distributed and delivered in optimal concentrations (5,6) . Computer-aided methods now permit dynamic study of myocardial contrast appearance-disappearance, yielding several potential indexes of perfusion (7) . In recognition of current limitations, efforts are under way to develop dedicated ultrasound instrumentation (8) . Contrast echocardiography is particularly well suited for detection and delin-
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ورودعنوان ژورنال:
- Journal of the American College of Cardiology
دوره 12 4 شماره
صفحات -
تاریخ انتشار 1988