Photothermal effect for localized desorption of primary lymphocytes arrayed on an antibody/DNA-based biochip.

نویسندگان

  • Loïc Leroy
  • Radoslaw Bombera
  • Elodie Engel
  • Roberto Calemczuk
  • Loïc Laplatine
  • Dieu-donné R Baganizi
  • Patrice N Marche
  • Yoann Roupioz
  • Thierry Livache
چکیده

This work proposes a miniaturized system able to perform multiple cell capture followed by cell-type selective release from a biochip surface. Unlabelled lymphocytes were first specifically captured onto a DNA array by antibody-DNA conjugates. The immobilized cells were subsequently released under spatiotemporal control within local heating generated by intense Surface Plasmon Resonance (SPR) produced by laser illumination.

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عنوان ژورنال:
  • Lab on a chip

دوره 14 12  شماره 

صفحات  -

تاریخ انتشار 2014