Olive leaf extract improves insulin sensitivity in overweight middle aged males; a randomized, double-blinded, placebo controlled, crossover trial
نویسندگان
چکیده
Method We conducted a randomized, double-blinded, placebo controlled, crossover trial on an overweight middle aged male population at risk of developing the metabolic syndrome comparing olive leaf extract containing 51 mg oleuropein and 9.7 mg hydroxytyrosol to placebo. We measured insulin sensitivity (Matsuda method), pancreatic b-cell responsiveness (oral disposition index), lipid profile, ambulatory blood pressure, carotid intimal media thickness, body composition (DEXA) basal metabolic rate, hand-grip strength, wellness questionnaire, inflammatory cytokines, antioxidant potential all measured at baseline and end of both interventions.
منابع مشابه
Olive (Olea europaea L.) Leaf Polyphenols Improve Insulin Sensitivity in Middle-Aged Overweight Men: A Randomized, Placebo-Controlled, Crossover Trial
BACKGROUND Olive plant leaves (Olea europaea L.) have been used for centuries in folk medicine to treat diabetes, but there are very limited data examining the effects of olive polyphenols on glucose homeostasis in humans. OBJECTIVE To assess the effects of supplementation with olive leaf polyphenols (51.1 mg oleuropein, 9.7 mg hydroxytyrosol per day) on insulin action and cardiovascular risk...
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ورودعنوان ژورنال:
دوره 2013 شماره
صفحات -
تاریخ انتشار 2013