Clinical, physiological and serological observations of a human following a venomous bite by Macrovipera lebetina lebetina (Reptilia: Serpentes).
نویسندگان
چکیده
A researcher, a 40 year-old male, was bitten on his finger accidentally by a 75 cm long, adult male blunt-nosed viper, Macrovipera lebetina lebetina (Linnaeus) that had been collected from northern Cyprus during laboratory work in the Zoology Section, Biology Department of the Ege University Faculty of Science. The clinical signs, physiological and biochemical changes soon after the venomous bite by the blunt-nosed viper as well as the electrophoretic separation of plasma proteins of the patient have been presented here. Serious important symptoms (edema, hypotension shock, hemorrhage, tissue necrosis, and melanoderma) developed and major quantitative differences in the fractions of albumin, globulin and albumin/globulin ratios were detected. On the other hand, the measurements carried out in blood smears and biochemical results indicated the decrease in RBC, MCV, MHV and a decrease in the diameter of red blood cells, as well as an increase in WBC.
منابع مشابه
Evaluation of Iranian Snake ‘Macrovipera lebetina’ Venom Cytotoxicity in Kidney Cell Line HEK-293
Background:Envenomation by Macrovipera lebetina (M. lebetina) is characterized by prominent local tissue damage, hemorrhage, abnormalities in the blood coagulation system, necrosis, and edema. However, the main cause of death after a bite by M. lebetina has been attributed to acute renal failure (ARF). It is unclear whether the venom components have a direct or indirect action in causing ARF. T...
متن کاملA serological comparison of the populations of the Levantine Viper, Macrovipera lebetina (Linnaeus, 1758) in Cyprus and Southern Turkey
The present study compares the blood-serum proteins of populations of the Levantine viper, Macrovipera lebetina L. from Cyprus and southern Anatolia by polyacrylamide gel electrophoresis and densitometry analysis methods. There were discernible differences found between the two populations for the blood serum protein features compared. By considering these differences, it is concluded that the ...
متن کاملDetermination of in vivo toxicity and in vitro cytotoxicity of venom from the Cypriot blunt-nosed viper Macrovipera lebetina lebetina and antivenom production
The venomous Levantine viper, Macrovipera lebetina lebetina is endemic to Cyprus. The objective of this study was to investigate in vitro cytotoxicity, in vivo lethality, and antivenom production followed by a re-immunization schedule in mice against Macrovipera lebetina lebetina venom. The LD50 value was estimated as 7.58mg/kg within 24 hours by different venom doses administrated intraperiton...
متن کاملCytotoxic Effect of Iranian Vipera Lebetina snake Venom on HUVEC Cells
Objective: Envenomation by heamotoxic snakes constituted a critical health occurrence in the world. Bleeding is the most sever consequence following snake bite with viperid and crothalid snakes. It is believed that the degradation of vascular membrane caused hemorrhage; in contrast, some suggested that direct cytotoxicity has role in endothelial cell disturbances. This study was to evaluate the...
متن کاملCytotoxic Effect of Iranian Vipera Lebetina snake Venom on HUVEC Cells
Objective: Envenomation by heamotoxic snakes constituted a critical health occurrence in the world. Bleeding is the most sever consequence following snake bite with viperid and crothalid snakes. It is believed that the degradation of vascular membrane caused hemorrhage; in contrast, some suggested that direct cytotoxicity has role in endothelial cell disturbances. This study was to evaluate the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Turkiye parazitolojii dergisi
دوره 30 2 شماره
صفحات -
تاریخ انتشار 2006