Marcumar [3-(1'-phenylpropyl)-4-hydroxycoumarin]; a new anticoagulant.
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چکیده
منابع مشابه
Coumarin derivatives from Ainsliaea fragrans and their anticoagulant activity
Coumarin derivatives are an important class of C6-C3 plant metabolites that show a variety of bioactivities. Currently, most clinical anticoagulant agents are coumarins, such as warfarin, dicoumarol and acenocoumarol, and patients taking these drugs must be monitored for adverse reactions. In a search for safe and effective anticoagulant compounds from Chinese herbal medicine, a screening proce...
متن کاملEffect of oral anticoagulant (marcumar) on prothrombin and related components in blood coagulation.
Marcumar has been considered as an excellent anticoagulant for long term management. It was found that the effect of the drug on plasma levels of prothiombin and autoprothrombin I and autoprothrombin II differed from that of the drugs previously studied using the technics described. Autoprothrombin II was not reduced by Marcumar. This clotting factor, autoprothrombin II, has been found to have ...
متن کاملProthrombin Activity in Rats with Mammary
The status of hepatic function can be altered by diverse influences. Multiple functional processes are measurably affected by several extrinsic toxic agents (typhoid toxin, chloroform, yellow phosphorus) as well as by a large number of pathological disorders. After exposure to toxins, in obstructive jaundice, in cirrhotic processes, in intrahepatic tumors and the like, either anatomical disrupt...
متن کاملProthrombin Activity in Rats with Mammary
The status of hepatic function can be altered by diverse influences. Multiple functional processes are measurably affected by several extrinsic toxic agents (typhoid toxin, chloroform, yellow phosphorus) as well as by a large number of pathological disorders. After exposure to toxins, in obstructive jaundice, in cirrhotic processes, in intrahepatic tumors and the like, either anatomical disrupt...
متن کاملProthrombin Activity in Rats with Mammary
The status of hepatic function can be altered by diverse influences. Multiple functional processes are measurably affected by several extrinsic toxic agents (typhoid toxin, chloroform, yellow phosphorus) as well as by a large number of pathological disorders. After exposure to toxins, in obstructive jaundice, in cirrhotic processes, in intrahepatic tumors and the like, either anatomical disrupt...
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ورودعنوان ژورنال:
- Circulation
دوره 10 5 شماره
صفحات -
تاریخ انتشار 1954