Following aptamer-ricin specific binding by single molecule recognition and force spectroscopy measurements.
نویسندگان
چکیده
Single molecule recognition imaging and dynamic force spectroscopy (DFS) analysis showed strong binding affinity between an aptamer and ricin, which was comparable with antibody-ricin interaction. Molecular simulation showed a ricin binding conformation with aptamers and gave different ricin conformations immobilizing on substrates that were consistent with AFM images.
منابع مشابه
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عنوان ژورنال:
- Chemical communications
دوره 48 11 شماره
صفحات -
تاریخ انتشار 2012