Berson, Yalow, and the JCI: the agony and the ecstasy.

It's about the journey, Not the destination: The birth of radioimmunoassay. 1960.

Featured Article: Yalow RS, Berson SA. Immunoassay of endogenous plasma insulin in man. J Clin Invest 1960;39:1157–75. They met in 1950. She was a 29-year-old researcher with a PhD in nuclear physics who had been accepted to graduate school only because there was a shortage of male students because of World War II. He was a 32-year-old physician who had collected more than 100 rejection letters...

Solomon A. Berson (1918-1972)

Solomon A. Berson helped develop the radioimmunoassay (RIA) technique in the US during the twentieth century. Berson made many scientific contributions while working with research partner Rosalyn Yalow at the Bronx Veterans Administration (VA) hospital, in New York City, New York. In the more than twenty years that Berson and Yalow collaborated, they refined the procedures for tracing diagnosti...

Paediatric lung transplantation: the agony and the ecstasy.

The insulin immunoassay after 50 years: a reassessment.

In 1960 Berson and Yalow published a method for the radioimmunoassay (RIA) of plasma insulin based on the concept that the extent to which unlabeled insulin displaces labeled insulin from anti-insulin antibody is proportional to the concentration of unlabeled insulin. The RIA for insulin has greatly increased knowledge of the physiology of glucose homeostasis and of the diverse causes of diabet...

Nucleotide metabolism in germinating seeds. The ribonucleic acid of Pisum arvense.

Marks, H. P. & Young, F. G. (1940). Nature, Lond., 14,8, 31. Morgan, H. E., Randle, P. J. & Regen, D. M. (1959). Biochem. J. 73, 573. Murad, F., Chi, Y. M., Rall, T. W. & Sutherland, E. W. (1962). J. biol. Chem. 237, 1233. Newey, H., Parsons, B. J. & Smyth, D. H. (1959). J. Physiol. 148, 83. Partridge, S. M. (1949). Nature, Lond., 164, 443. Pozza, G., Galansino, G., Hoffeld, H. & Foa, P. P. (19...