Intention-to-treat principle.
نویسندگان
چکیده
منابع مشابه
Applying the intention-to-treat principle in practice: Guidance on handling randomisation errors
BACKGROUND The intention-to-treat principle states that all randomised participants should be analysed in their randomised group. The implications of this principle are widely discussed in relation to the analysis, but have received limited attention in the context of handling errors that occur during the randomisation process. The aims of this article are to (1) demonstrate the potential pitfa...
متن کاملInclusion of patients in clinical trial analysis: the intention-to-treat principle.
The Medical Journal of Australia ISSN: 0025-729X 20 October 2003 179 8 438-440 ©The Medical Journal of Australia 2003 www.mja.com.au EBM: Trials on Trial DETERMINING THE SAMPLE OF PARTICIPANTS to be analysed is a crucial step in reporting clinical trials. For such analyses, the gold standard is the “intention-to-treat” principle. The question of which participants are included in the analysis a...
متن کاملUnderstanding the Intention-to-treat Principle in Randomized Controlled Trials
Clinicians, institutions, and policy makers use results from randomized controlled trials to make decisions regarding therapeutic interventions for their patients and populations. Knowing the effect the intervention has on patients in clinical trials is critical for making both individual patient as well as population-based decisions. However, patients in clinical trials do not always adhere to...
متن کاملمقایسه اعتبار دو روش مبتنی بر پروتکل و مبتنی بر قصد درمان با استفاده از شبیه‌سازی مونت کارلو: تحلیل ثانویه یک کارآزمایی بالینی در درمان بیماران اسکیزوفرنی در حضور عدم اجابت بیماران از دوز کامل دارو
Background & Objectives: The standard methods for the comparison of two drugs in a randomized controlled clinical trial in the presence of non-compliance are intention-to-treat or per-protocol approaches. Both approaches have problems with estimation of drug effects, and researchers are not still certain to adopt which one. In this study, the bias of intention-to-treat and per-protocol approach...
متن کاملQuality of reporting of randomized trials as a measure of methodologic quality.
CONTEXT The evaluation of the methodologic quality of randomized controlled trials (RCTs) is central to evidence-based health care. Important methodologic detail may, however, be omitted from published reports, and the quality of reporting is therefore often used as a proxy measure for methodologic quality. We examined the relationship between reporting quality and methodologic quality of publi...
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عنوان ژورنال:
- CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
دوره 165 10 شماره
صفحات -
تاریخ انتشار 2001