Pathogenesis and Preventive Strategies of Chronic Dysfunction of Renal Allograft
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چکیده
منابع مشابه
Regulatory T Cell Subtypes and TGF-β1 Gene Expression in Chronic Allograft Dysfunction
Background: Regulatory T cells have been suggested to have a protective role against acute rejection in allograft recipients. However, there is little information available about their contribution to chronic rejection process. The role of transforming growth factor-beta 1 (TGF- β1) as a profibrogenic and/or immunoregulatory cytokine in renal allografts is also controversial. Objectives: To eva...
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Background: The incidence of ischemic reperfusion injury (IRI) in early phase post-transplantation and activation of toll-like receptor (TLR-2) and TLR-4 remarkably impact the outcome of a renal allograft. Objective: To investigate whether the expression of TLRs in peripheral blood mononuclear cells (PBMCs) can predict the clinical outcome of kidney allografts. Methods: We obtained blood sample...
متن کاملنارسایی طولانی مدت عملکرد کلیه در بیماران پیوندی با اختلال عملکرد مزمن
HR Khalkhali [1] , MSc E Hajizadeh [2] , PhD A Ghafari Moghadam [3] , MD A Kazemnezhad [4] , PhD Morad Hajiyan [5] , MSc Received: 21 April, 2009 Accepted: 22 July, 2009 Abstract Background & Aims: Chronic Allograft Dysfunction is a major concern for graft loss in Renal Transplant Recipients. This paper investigated the waiting time and death-censored graft survival in renal transplant ...
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INTRODUCTION Kidney transplantation is the treatment of choice for patients with end-stage renal disease. Despite great progress in surgical aspects and immunosupression therapy, long-term graft survival has not been consistent. Chronic allograft dysfunction (CAD) remains a major cause of late grafts failure. REVIEW CAD is a generic term of all causes of chronic renal allograft dysfunction as...
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