Mutations in a 23S rRNA gene of Chlamydia trachomatis associated with resistance to macrolides.
نویسندگان
چکیده
For six clinical isolates of Chlamydia trachomatis, in vitro susceptibility to erythromycin, azithromycin, and josamycin has been determined. Four isolates were resistant to all the antibiotics and had the mutations A2058C and T2611C (Escherichia coli numbering) in the 23S rRNA gene. All the isolates had mixed populations of bacteria that did and did not carry 23S rRNA gene mutations.
منابع مشابه
Detection of A2142C, A2142G, and A2143G Mutations in 23s rRNA Gene Conferring Resistance to Clarithromycin among Helicobacter pylori Isolates in Kerman, Iran
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 48 4 شماره
صفحات -
تاریخ انتشار 2004