Reproductive Outcome in Women with Congenital Uterine Anomalies

Background: Mullerian duct malformations delineate a group of congenital anomalies that result from arrested development, or incomplete fusion of the mesonephric ducts. In many patients, uterine anomalies have been related with infertility, recurrent pregnancy loss, prematurity and other obstetric complications which increase perinatal morbidity and mortality rates, where as in others these malformations are asymptomatic and have normal reproductive performance. Purpose: To determine the reproductive outcome in women with congenital uterine anomalies. Design: Descriptive cross sectional survey. Main Outcome Measures: Miscarriages, Preterm delivery, Ecotpic pregnancy, Term delivery. Material and Methods: A total of 1600 infertile women in the age group of 25 – 35 years were recruited in the outpatient department of Gynae and Obstetrics in Sharif Medical City Hospital from June, 2008 to June, 2009. The patients included in study were the women presenting with either primary or secondary infertility, bad obstetrical history, recurrent miscarriage, preterm deliveries, and ectopic pregnancies. Combined finding of trans-vaginal ultrasonography and hysterosalpingography were used to diagnose congenital uterine anomalies. 48 women were diagnosed with congenital uterine anomalies. Eight patients of primary infertility with uterine anomalies were excluded. The retrospective analysis of 40 cases with secondary infertility and uterine anomalies was done for