Text S1 Constructing The Energy Landscape for Genetic Switching System Driven by Intrinsic Noise: Supporting Information

نویسندگان

  • Cheng Lv
  • Xiaoguang Li
  • Fangting Li
  • Tiejun Li
چکیده

I. Mean field limit of CMEs II. Comparison of Hamiltonian III. Scale independence on the choice of system size IV. Introduction of the gMAM IV-A. The Outer Loop IV-B. Evaluating the Action IV-C. The Inner Loop (Computing θ̂(φ,φ′)) V.Stochastic Simulation V-A. Transition Trajectory from MC Simulation V-B. Mean Switching Time (MST) from MC simulation V-C. Local Property: Fluctuation around Stable States VI. Analysis of Uphill Path VII. Application in Transcriptional Cascades

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تاریخ انتشار 2014