Sterically demanding imidazolinium salts through the activation and cyclization of formamides.
نویسندگان
چکیده
A new protocol was developed for the synthesis of sterically demanding imidazolinium salts. This procedure was adopted for the synthesis of seven NHC salts, including ones that were demonstrated to be inaccessible using the conventional orthoformate ester type cyclization method.
منابع مشابه
Tailor-made synthesis of various backbone-substituted imidazolinium salts by triflic anhydride mediated intramolecular cyclisation.
We have found a Tf(2)O-mediated intramolecular cyclization reaction and have revealed an intriguing stereoselectivity and a regioselectivity during the preparation of intermediate alcohols, which allow for the tailor-made synthesis of various backbone-substituted imidazolinium salts, and structurally specific syn-4,5-disubstituted imidazolinium salts.
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متن کاملA facile preparation of backbone-substituted, functionalized and chiral imidazolinium salts.
A versatile and modular method for the preparation of various backbone-substituted, functionalized and chiral imidazolinium salts from the reaction of formamidines with alkene oxides has been described, providing a more straightforward access to substituted imidazolinium salts than the previously reported methods.
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 83 شماره
صفحات -
تاریخ انتشار 2012