Mistletoe lectin is not the only cytotoxic component in fermented preparations of Viscum album from white fir (Abies)
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Mistletoe lectin is not the only cytotoxic component in fermented preparations of Viscum album from white fir (Abies pectinata)
BACKGROUND Preparations of mistletoe (Viscum album) are the form of cancer treatment that is most frequently used in the complementary medicine. Previous work has shown that these preparations are able to exert cytotoxic effects on carcinoma cells, the extent of which might be influenced by the host tree species and by the content of mistletoe lectin. METHODS Using colorimetric assays, we hav...
متن کاملPaediatric medulloblastoma cells are susceptible to Viscum album (Mistletoe) preparations.
BACKGROUND Medulloblastoma constitute more than 20% of all paediatric brain tumours and are the most common malignant brain tumours in children. Adjuvant chemotherapy has seen a strong increase in the use of complementary medicine for cancer treatment. Evidence for cytotoxic and apoptotic effects of Viscum album (Mistletoe) in vitro is available, however, no data concerning paediatric tumours, ...
متن کاملDwarf mistletoe-host interactions in mixed-conifer forests in the sierra nevada.
ABSTRACT We determined the spatial pattern of dwarf mistletoe (Arceuthobium spp.) associated with two different conifer hosts, white fir (Abies concolor) and Jeffrey pine (Pinus jeffreyi), in forests around the Lake Tahoe Basin and at the Teakettle Experimental Forest, both located in the Sierra Nevada. We also examined a number of host variables and bark beetle incidence to determine how these...
متن کاملAntitumor and antibacterial activities of Viscum album L. grown on different host trees Farklı konakçı ağaçlarda yetişen Viscum album L.’nin antitümör ve antibakteriyel aktiviteleri
AIM: The present study aims to investigate for the first time antitumor and antibacterial activities of Viscum album L. grown on different host trees. METHODS: Two different bioassays (antitumor and antibacterial) were performed to evaluate the biological activities of European mistletoe (Viscum album L.) plants collected from 13 different host trees (Crataegus tanacetifolia, Crataegus monogyna...
متن کاملInhibition of protein synthesis by a toxic lectin from Viscum album L. (mistletoe).
1. The haemagglutinating and toxic lectin from Viscum album L. (mistletoe) inhibits protein synthesis in a lysate of rabbit reticulocytes, with an ID50 (concentration giving 50% inhibition) of 2.6 microgram/ml. This effect is enhanced (ID50 0.21 microgram/ml) if the lectin is reduced with 2-mercaptoethanol. 2. The lectin inhibits protein synthesis also in BL8L cells in culture. Inhibition occur...
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