Cerebellar hypoplasia in Werdnig-Hoffmann disease.
نویسنده
چکیده
The case of an infant with Werding-Hoffmann disease, who died at the age of 4 1/2 days, is reported. At autopsy there was severe cerebellar hypoplasia, associated with degenerative changes in the brain-stem nuclei. This case supports the concept that cerebellar hypoplasia may develop as a manifestation of the neuronal abiotrophy of Werdnig-Hoffmann disease. A similarity has been noted between the cerebellar lesion found in the child reported here and that produced by viral infection in experimental animals.
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ورودعنوان ژورنال:
- Developmental medicine and child neurology
دوره 17 4 شماره
صفحات -
تاریخ انتشار 1961