Mixed Medullary - Follicular Thyroid Carcinoma : A Report of Two Cases
نویسندگان
چکیده
Mixed medullary-follicular carcinoma is an uncommon tumor of the thyroid. It is characterized by histological and immunohistochemical features of both follicular and parafollicular C cells. We report two female patients, aged 26 and 78 years, with mixed medullary-follicular carcinoma. Histologically, the tumors are composed of follicular carcinoma areas and solid nests of polygonal cells consistent with medullary carcinoma. Immunohistochemically, thyroglobulin and calcitonin positivity was detected. Precise diagnosis of mixed medullary-follicular carcinoma is essential for accurate treatment and follow-up.
منابع مشابه
Mixed medullary-papillary carcinoma of the thyroid: a case report.
With fewer than 40 cases described in the otolaryngology literature, mixed medullary papillary thyroid carcinoma represents a rare but phenotypically distinct tumor. While isolated medullary carcinoma may be admixed with normal follicular structures, true mixed carcinoma displays morphological and immunological characteristics of medullary and papillary carcinoma within a single lesion. We repo...
متن کاملMedullary Thyroid Cancer: A Review
Thyroid cancer is a malignancy of the thyroid parenchymal cells. There are four main types of thyroid cancer: papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), anaplastic thyroid carcinoma (ATC), and Medullary thyroid carcinoma (MTC). Medullary thyroid cancer (MTC) is a rare neuroendocrine tumor of the thyroid gland derived from parafollicular C-cells that produce calcitonin (CT...
متن کاملA Patient with Synchronous Follicular (Hurthle Cell), Papillary, and Medullary Thyroid Carcinomas: A Case Report with Literature Review on Possible Incidence and Pathogenesis
This case report is the fourth case documented of a patient with synchronous Follicular, Papillary, and Medullary Thyroid Carcinoma. There have been several case series in the last two decades that include either concurrent papillary-medullary or follicular-medullary thyroid carcinoma, but only three cases documented for all three of these types of thyroid carcinomas occurring in the same patie...
متن کاملMixed medullary-follicular carcinoma and papillary carcinoma of the same thyroid.
We report a rare case of mixed medullary-follicular carcinoma and papillary carcinoma of the same thyroid. A 27-year-old Chinese female complained of a single thyroid nodule for 2-3 months. Needle aspiration revealed suspicious papillary carcinoma and thyroidectomy performed later showed mixed medullary-follicular carcinoma and papillary carcinoma of the same thyroid which was extremely rare. W...
متن کاملOncocytic Variant Of Medullary Thyroid Carcinoma - A Case Report
Medullary thyroid carcinoma (MTC) is a rare tumor arising from parafollicular C-cells. The oncocytic variant of MTC is an extremely rare diagnosis, with less than 20 cases reported. Here we present the case of a 36-year-old male patient with complaints of neck swelling and dysphagia. On fine needle aspiration cytology (FNAC), a Hürthle cell neoplasm was suggested. Finally with histopathol...
متن کامل