Forging a potent vaccine adjuvant: CpG ODN/cationic peptide nanorings

نویسندگان

  • Bilgi Gungor
  • Fuat Cem Yagci
  • Ihsan Gursel
  • Mayda Gursel
چکیده

Type I interferon inducers may potentially be engineered to function as antiviral and anticancer agents, or alternatively, vaccine adjuvants, all of which may have clinical applications. We recently described a simple strategy to convert a Toll-like receptor 9 (TLR9) agonist devoid of interferon α (IFNα) stimulating activity into a robust Type I interferon inducer with potent vaccine adjuvant activity.

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عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2014